Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | DHODH | Q02127 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169360 | 0.90 | DHODH (0.42) | ALDH1A1DHODH | |
| SCHEMBL7698327 | 0.89 | PLA2G2A (0.42) | GAAALDH1A1POLBDHODH | |
| SCHEMBL7703694 | 0.87 | KDM4E (0.41) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL38662579 | 0.79 | MEN1 (0.48) | MEN1KMT2AGAANPC1RAB9A | |
| SCHEMBL8169049 | 0.79 | KDM4E (0.43) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7701145 | 0.78 | GABRA1 (0.46) | MEN1KMT2AGAANPC1RAB9A | |
| SCHEMBL4763668 | 0.77 | LMNA (0.45) | KMT2AALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL7702922 | 0.76 | PDE3B (0.41) | MEN1KMT2APDE10AKDM4EALDH1A1 | |
| SCHEMBL7706778 | 0.72 | PLA2G2A (0.46) | GAAKDM4EALDH1A1POLBDHODH | |
| SCHEMBL2991023 | 0.72 | MEN1 (0.42) | MEN1KMT2AGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915851-B1 | DIBENZODIHYDROPYRIDINECARBOXYLIC ESTERS AND THEIR USE IN CHEMILUMINESCENT ASSAY METHODS | NEDERLANDEN STAAT (NL) | 2002-03-20 | — | — | EP | disclosed |
| US-6030803-A | FOR USE AS SUBSTRATE IN PEROXIDASE ASSAYS; ALPHA-CARBON ATOM OF THE ESTER ALKYL GROUP IS AN ALIPHATIC CARBON ATOM | DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGESZONHEID EN CULTUUR (NL) | 2000-02-29 | — | — | US | disclosed |