Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703348 | 0.89 | PLA2G2A (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7698330 | 0.88 | PLA2G2A (0.45) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7702282 | 0.86 | ALOX15 (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7703696 | 0.86 | KDM4E (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9944375 | 0.79 | MEN1 (0.58) | KMT2AMEN1PDE10AKDM4EALDH1A1 | |
| SCHEMBL7701142 | 0.78 | MEN1 (0.40) | KMT2AMEN1PDE10AKDM4EALDH1A1 | |
| SCHEMBL8169053 | 0.77 | PLA2G2A (0.47) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL2991023 | 0.75 | MEN1 (0.42) | KMT2AMEN1PDE10AKDM4EALDH1A1 | |
| SCHEMBL4421304 | 0.74 | KMT2A (0.50) | KMT2AMEN1PDE10AKDM4EALDH1A1 | |
| SCHEMBL4763671 | 0.74 | TSHR (0.57) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915851-B1 | DIBENZODIHYDROPYRIDINECARBOXYLIC ESTERS AND THEIR USE IN CHEMILUMINESCENT ASSAY METHODS | NEDERLANDEN STAAT (NL) | 2002-03-20 | — | — | EP | disclosed |
| US-6030803-A | FOR USE AS SUBSTRATE IN PEROXIDASE ASSAYS; ALPHA-CARBON ATOM OF THE ESTER ALKYL GROUP IS AN ALIPHATIC CARBON ATOM | DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGESZONHEID EN CULTUUR (NL) | 2000-02-29 | — | — | US | disclosed |
| US-6018047-A | GROUP Z-A-AT POSITION 10, WHERE A IS A DIVALENT ORGANIC MOIETY AND Z IS CAPABLE OF COUPLING A BIOACTIVE COMPOUND, AND AT POSITION 9 AN ESTER WHICH FORMS DIOXETANE WITH HYDROGEN PEROXIDE; USE IN HETEROGENEOUS AND HOMOGENEOUS IMMUNOASSAYS | ZOMER GIJSBERT (NL) | 2000-01-25 | — | — | US | disclosed |
| US-5521103-A | Acridinium compounds as chemiluminogenic label | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0324202-B1 | Acridinium compounds as chemiluminogenic label | MOCHIDA PHARM CO LTD (JP) | 1994-08-24 | — | — | EP | disclosed |
| EP-0324202-A1 | Acridinium compounds as chemiluminogenic label | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-19 | — | — | EP | disclosed |