Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700530 | 0.90 | MTNR1A (0.32) | MTNR1ATP53KMT2A | |
| SCHEMBL7701095 | 0.85 | CA9 (0.35) | TP53KMT2AMAPTCA12CA9 | |
| SCHEMBL7697135 | 0.84 | PARP1 (0.43) | KMT2A | |
| SCHEMBL7700710 | 0.84 | KMT2A (0.31) | KMT2AMEN1 | |
| SCHEMBL7700274 | 0.84 | TP53 (0.30) | TP53KMT2A | |
| SCHEMBL7700732 | 0.84 | SLC9A1 (0.36) | KMT2A | |
| SCHEMBL7701257 | 0.83 | KMT2A (0.31) | KMT2ACA9 | |
| SCHEMBL7694853 | 0.83 | PARP1 (0.34) | KMT2A | |
| SCHEMBL7700305 | 0.83 | KMT2A (0.36) | MTNR1ATP53KMT2AMEN1MAPT | |
| SCHEMBL7700277 | 0.82 | SLC9A1 (0.34) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346527-B1 | 1-BENZOXEPIN DERIVATIVES USED IN THE PREVENTION OF SODIUM AND HYDROGEN ION EXCHANGE; CARDIOVASCULAR, KIDNEY AND BRAIN DISORDER TREATMENT; ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-12 | — | — | US | disclosed |