Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699494 | 0.90 | NPC1 (0.58) | GAAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7695399 | 0.85 | KDM4E (0.51) | GAAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7699717 | 0.85 | HPGD (0.54) | GAAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7698680 | 0.85 | MAPT (0.53) | GAAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7693531 | 0.85 | KCNQ3 (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL7698117 | 0.82 | NPC1 (0.57) | GAAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7700629 | 0.81 | NPC1 (0.48) | GAAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7698274 | 0.81 | RAB9A (0.51) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7704827 | 0.80 | NPC1 (0.55) | GAAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7705439 | 0.80 | KDM4E (0.50) | GAAALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |