Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701405 | 0.87 | NPC1 (0.56) | MAPTHTTKDM4ETSHRHPGD | |
| SCHEMBL7700048 | 0.87 | NPC1 (0.50) | MAPTHTTKDM4EMEN1KMT2A | |
| SCHEMBL7697078 | 0.85 | HPGD (0.56) | MAPTLMNAKDM4ETSHRMEN1 | |
| SCHEMBL7701371 | 0.85 | GAA (0.48) | MAPTHTTLMNATOP2ATOP2B | |
| SCHEMBL7703221 | 0.85 | RAB9A (0.67) | MAPTKDM4EMEN1KMT2AHPGD | |
| SCHEMBL7701952 | 0.83 | MAPT (0.54) | MAPTHTTLMNAKDM4EKMT2A | |
| SCHEMBL7698887 | 0.82 | ALDH1A1 (0.49) | MAPTHTTMEN1KMT2AHPGD | |
| SCHEMBL7694301 | 0.82 | RAB9A (0.52) | MAPTHTTKDM4EMEN1KMT2A | |
| SCHEMBL7698683 | 0.82 | MAPT (0.52) | MAPTHTTKDM4EMEN1KMT2A | |
| SCHEMBL7701153 | 0.82 | ALDH1A1 (0.63) | MAPTHTTLMNAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |