Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315951 | 0.77 | TDP1 (0.33) | ALDH1A1 | |
| SCHEMBL25408012 | 0.73 | MAPK8 (0.33) | MAPK8DYRK1ACLK4DYRK1BXDH | |
| SCHEMBL11029949 | 0.72 | SMN1; SMN2 (0.33) | MAPK8DYRK1ACLK4DYRK1BTBXAS1 | |
| SCHEMBL7702569 | 0.68 | XDH (0.33) | XDHALDH1A1 | |
| SCHEMBL11306298 | 0.67 | PDE5A (0.49) | ALDH1A1 | |
| SCHEMBL21434271 | 0.64 | GSK3A (0.36) | ALDH1A1 | |
| SCHEMBL25410369 | 0.64 | CHEK1 (0.37) | XDHALDH1A1 | |
| SCHEMBL31687853 | 0.63 | CHEK1 (0.32) | — | |
| SCHEMBL31136330 | 0.61 | TNKS (0.33) | ALDH1A1 | |
| SCHEMBL7704795 | 0.60 | ALDH1A1 (0.32) | XDHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081473-A1 | SUBSTITUTED AZOLOAZIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2002-10-17 | — | — | WO | disclosed |
| US-RE30511-E | ENZYME INHIBITOR, HERBICIDE, CYCLIZATION | AMERICAN CYANAMID COMPANY (US) | 1981-02-10 | — | — | US | disclosed |
| US-4168964-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
| US-4124766-A | INTERMEDIATES FOR PHOSPHODIESTERASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-11-07 | — | — | US | disclosed |
| US-4107307-A | ENZYME INHIBITORS, HERBICIDES, RING CLOSURE | AMERICAN CYANAMID COMPANY (US) | 1978-08-15 | — | — | US | disclosed |