Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694001 | 0.90 | MAPT (0.58) | DGAT1L3MBTL1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7695331 | 0.88 | USP2 (0.57) | DGAT1L3MBTL1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7699467 | 0.88 | ALDH1A1 (0.52) | DGAT1L3MBTL1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7699897 | 0.88 | L3MBTL1 (0.51) | DGAT1L3MBTL1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7701794 | 0.87 | SMN1; SMN2 (0.53) | DGAT1L3MBTL1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7697962 | 0.87 | L3MBTL1 (0.56) | DGAT1L3MBTL1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7701952 | 0.86 | MAPT (0.54) | DGAT1L3MBTL1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7703324 | 0.84 | L3MBTL1 (0.53) | DGAT1L3MBTL1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7696391 | 0.84 | MAPT (0.54) | DGAT1L3MBTL1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7695770 | 0.83 | MAPT (0.58) | DGAT1L3MBTL1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |