Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701952 | 0.90 | MAPT (0.54) | USP2HTTLMNAMAPTSMN1; SMN2 | |
| SCHEMBL7699467 | 0.88 | ALDH1A1 (0.52) | USP2MAPTSMN1; SMN2L3MBTL1DGAT1 | |
| SCHEMBL7699897 | 0.88 | L3MBTL1 (0.51) | USP2LMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7701960 | 0.88 | DGAT1 (0.52) | HTTLMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7701794 | 0.88 | SMN1; SMN2 (0.53) | HTTMAPTSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL7697962 | 0.88 | L3MBTL1 (0.56) | MAPTSMN1; SMN2POLBL3MBTL1DGAT1 | |
| SCHEMBL7701316 | 0.87 | DGAT1 (0.49) | USP2HTTLMNAMAPTSMN1; SMN2 | |
| SCHEMBL7694001 | 0.86 | MAPT (0.58) | HTTLMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7703324 | 0.85 | L3MBTL1 (0.53) | MAPTSMN1; SMN2POLBL3MBTL1DGAT1 | |
| SCHEMBL7696391 | 0.85 | MAPT (0.54) | USP2HTTMAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |