Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702569 | 0.78 | XDH (0.33) | ALDH1A1PARP10 | |
| SCHEMBL12032371 | 0.60 | JAK1 (0.41) | — | |
| SCHEMBL19939421 | 0.59 | DRD2 (0.36) | KDM4EALDH1A1HPGDAPOBEC3G | |
| SCHEMBL844319 | 0.56 | — | — | |
| SCHEMBL21266779 | 0.54 | ADORA2A (0.30) | — | |
| SCHEMBL13201561 | 0.53 | CLK4 (0.38) | KDM4EMAPTGAA | |
| SCHEMBL25410369 | 0.52 | CHEK1 (0.37) | KDM4EALDH1A1MAPTPKMHPGD | |
| SCHEMBL14341720 | 0.51 | KDM4E (0.32) | KDM4EALDH1A1HPGD | |
| SCHEMBL21863289 | 0.51 | MAPT (0.40) | KDM4EALDH1A1MAPTALOX15LMNA | |
| SCHEMBL15450971 | 0.50 | NOS3 (0.34) | MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081473-A1 | SUBSTITUTED AZOLOAZIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2002-10-17 | — | — | WO | disclosed |
| US-RE30511-E | ENZYME INHIBITOR, HERBICIDE, CYCLIZATION | AMERICAN CYANAMID COMPANY (US) | 1981-02-10 | — | — | US | disclosed |
| US-4168964-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
| US-4124766-A | INTERMEDIATES FOR PHOSPHODIESTERASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-11-07 | — | — | US | disclosed |
| US-4107308-A | HYPOTENSIVE AGENTS, HERBICIDES, REACTING SODIUM SALT WITH ALLYL OR ALKYL HALIDE, RING CLOSURE | AMERICAN CYANAMID COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-4107307-A | ENZYME INHIBITORS, HERBICIDES, RING CLOSURE | AMERICAN CYANAMID COMPANY (US) | 1978-08-15 | — | — | US | disclosed |