Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2841040 | 0.81 | ALDH1A1 (0.42) | CA2CA1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL28555537 | 0.75 | CA2 (0.41) | CA2CA1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL30150307 | 0.73 | NR5A2 (0.38) | SMN1; SMN2LMNATSHRMAPTCYP1A2 | |
| SCHEMBL7031654 | 0.73 | FFAR1 (0.50) | ALDH1A1PTGS2PTGS1LMNACYP3A4 | |
| SCHEMBL5804625 | 0.72 | GPR84 (0.48) | TYRALOX5TSHRMAPTALOX15 | |
| SCHEMBL8848221 | 0.72 | FFAR1 (0.43) | FFAR1FFAR4 | |
| SCHEMBL11612127 | 0.72 | NR5A2 (0.38) | SMN1; SMN2PTGS2ALOX5PTGS1LMNA | |
| SCHEMBL29216781 | 0.71 | CA2 (0.40) | CA2CA1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL29216782 | 0.71 | CA2 (0.40) | CA2CA1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL29216783 | 0.71 | CA2 (0.40) | CA2CA1ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4708966-A | SUBSTITUTED DI-TERT-BUTYL PHENOL DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1987-11-24 | — | — | US | claimed |
| CN-118078513-A | Ostomy insert based on laser scanning technology and processing method and using method thereof | 飞鱼(山西)数字产业科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-6420428-B1 | TREATING HEPATITIS C AND HEPATIC FIBROSIS USING 2,6-DI-TERT-BUTYLPHENOL DERIVATIVES; EFFECTIVE IN SUBJECTS WITH INTERFERON INSUSCEPTIBILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-07-16 | — | — | US | disclosed |
| US-6369097-B1 | Treatment and prevention of hepatic disorders | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-04-09 | — | — | US | disclosed |
| US-6348493-B1 | TREATMENT OF HEPATITIS C BY ADMINISTERING 2,6-DI-TER-BUTYLPHENOL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-02-19 | — | — | US | disclosed |
| US-6218437-B1 | ADMINISTERING A THERAPEUTIC AMOUNT OF DI-TERT-BUTYLPHENOL DERIVATIVE TO SUBJECT UNDER CONDITIONS SUCH THAT SAID SYMPTOMS ARE DIMINISHED | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-04-17 | — | — | US | disclosed |
| WO-2001021166-A1 | TREATMENT AND PREVENTION OF HEPATIC DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-03-29 | — | — | WO | disclosed |
| EP-0251408-B1 | NOVEL ANTI-INFLAMMATORY AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR REDUCING INFLAMMATION | THE PROCTER & GAMBLE COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4708966-A | SUBSTITUTED DI-TERT-BUTYL PHENOL DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1987-11-24 | — | — | US | disclosed |