Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700673 | 0.86 | ALDH1A1 (0.46) | TSHRHPGDSMN1; SMN2CA1CA2 | |
| SCHEMBL7699828 | 0.77 | NPC1 (0.48) | TSHRNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7669067 | 0.71 | MAPT (0.67) | POLBTSHRNPC1RAB9AHPGD | |
| SCHEMBL19846082 | 0.70 | POLB (0.47) | POLBNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3884518 | 0.68 | HTR6 (0.61) | POLBTSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL20198361 | 0.66 | ALDH1A1 (0.54) | POLBTSHRSMN1; SMN2MAPTMCL1 | |
| (Phenylsulfonyl)Benzene SCHEMBL6912665 | 0.63 | HTR6 (0.74) | POLBTSHRSMN1; SMN2CA1CA2 | |
| SCHEMBL29012669 | 0.63 | RAB9A (0.79) | POLBTSHRNPC1RAB9AHPGD | |
| SCHEMBL30414780 | 0.63 | RAB9A (0.79) | POLBTSHRNPC1RAB9AHPGD | |
| SCHEMBL5609956 | 0.63 | NPC1 (0.46) | POLBTSHRNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |