Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702152 | 0.86 | POLB (0.49) | ALDH1A1MAPK1NPSR1TSHRHSD17B10 | |
| SCHEMBL7699828 | 0.80 | NPC1 (0.48) | ALDH1A1MAPK1NPSR1TSHRHSD17B10 | |
| SCHEMBL2097865 | 0.69 | RAB9A (0.43) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL5609956 | 0.67 | NPC1 (0.46) | ALDH1A1TSHRHSD17B10HPGDMAPT | |
| SCHEMBL3023976 | 0.67 | HTR6 (0.42) | ALDH1A1MAPK1HSD17B10MEN1KMT2A | |
| (Phenylsulfonyl)Benzene SCHEMBL2148473 | 0.66 | HTR6 (0.82) | ALDH1A1TSHRHSD17B10MAPTHTR6 | |
| SCHEMBL7702622 | 0.66 | ALDH1A1 (0.59) | ALDH1A1MAPK1NPSR1TSHRHSD17B10 | |
| (Phenylsulfonyl)Benzene SCHEMBL4982378 | 0.64 | HTR6 (0.88) | ALDH1A1TSHRHSD17B10MAPTHTR6 | |
| (Phenylsulfonyl)Benzene SCHEMBL30255 | 0.63 | HTR6 (1.00) | ALDH1A1MAPK1TSHRHSD17B10MAPT | |
| (Phenylsulfonyl)Benzene SCHEMBL13735236 | 0.63 | HTR6 (1.00) | ALDH1A1MAPK1TSHRHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |