Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700300 | 0.81 | ALDH1A1 (0.33) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL10885406 | 0.80 | ALDH1A1 (0.36) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL7945820 | 0.80 | PGK1 (0.37) | — | |
| SCHEMBL11217789 | 0.74 | CYP3A4 (0.35) | — | |
| SCHEMBL232176 | 0.73 | ALDH1A1 (0.42) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL3052064 | 0.73 | ALDH1A1 (0.48) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL28163418 | 0.70 | ALDH1A1 (0.32) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL394179 | 0.69 | — | — | |
| SCHEMBL3255153 | 0.69 | PGK1 (0.44) | HSD17B10 | |
| SCHEMBL5488004 | 0.69 | ALDH1A1 (0.44) | ALDH1A1CYP1A2ALOX15CASP7HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355826-B1 | HALOMETHYLATION AN AROMATIC ALDEHYDE COMPOUND AND SALT FORMATION | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-03-12 | — | — | US | disclosed |
| US-6252009-B1 | CROSSLINKING ACRYLONITRILE WITH DIISOCYANATE | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-06-26 | — | — | US | disclosed |
| EP-0903338-A2 | Synthesis of stable nitrile oxide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-03-24 | — | — | EP | disclosed |