Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL7702492

C[n+]1c2ccccc2c(C(=O)OC(C(F)(F)F)(C(F)(F)F)C(F)(F)F)c2cc(Cl)ccc21.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.35

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Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.35
ACHE P22303 6/20 0.32
TERT O14746 1/20 0.32
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30
PTGDR2 Q9Y5Y4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL7699753 0.88 LMNA (0.35) KCNH2TERTNR1H2NR1H3PTGDR2
Trifluoromethanesulfonic Acid SCHEMBL7706736 0.88 KCNH2 (0.33) KCNH2TERTNR1H2NR1H3
Trifluoromethanesulfonic Acid SCHEMBL7706738 0.85 KCNH2 (0.35) KCNH2ACHETERTNR1H2NR1H3
Trifluoromethanesulfonic Acid SCHEMBL7793780 0.78 KCNH2 (0.35) KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL7703830 0.78 ACHE (0.34) KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL2996949 0.78 ACHE (0.42) KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL7702380 0.77 ACHE (0.31) ACHETERT
Trifluoromethanesulfonic Acid SCHEMBL38661998 0.77 ACHE (0.36) KCNH2ACHE
SCHEMBL11784139 0.76 PLA2G2A (0.46)
Trifluoromethanesulfonic Acid SCHEMBL7796557 0.76 CYP1A2 (0.35) KCNH2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0915851-B1 DIBENZODIHYDROPYRIDINECARBOXYLIC ESTERS AND THEIR USE IN CHEMILUMINESCENT ASSAY METHODS NEDERLANDEN STAAT (NL) 2002-03-20 EP disclosed
US-6030803-A FOR USE AS SUBSTRATE IN PEROXIDASE ASSAYS; ALPHA-CARBON ATOM OF THE ESTER ALKYL GROUP IS AN ALIPHATIC CARBON ATOM DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGESZONHEID EN CULTUUR (NL) 2000-02-29 US disclosed