Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 13/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | CCR3 | P51677 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695531 | 0.94 | CCR2 (0.52) | CCR2SLC2A1OPRM1OPRK1OPRL1 | |
| SCHEMBL7702544 | 0.90 | CCR2 (0.62) | CCR2SLC2A1 | |
| SCHEMBL7700299 | 0.88 | CCR2 (0.49) | CCR2SLC2A1KCNH2OPRM1OPRK1 | |
| SCHEMBL7703003 | 0.86 | CCR2 (0.62) | CCR2SLC2A1OPRM1OPRK1OPRL1 | |
| SCHEMBL7701596 | 0.84 | CCR2 (0.51) | CCR2 | |
| SCHEMBL7700045 | 0.84 | CCR2 (0.56) | CCR2SLC2A1 | |
| SCHEMBL7699076 | 0.83 | CCR2 (0.52) | CCR2 | |
| SCHEMBL7695961 | 0.83 | HTR1D (0.54) | CCR2 | |
| SCHEMBL7696192 | 0.82 | CCR2 (0.58) | CCR2SLC2A1 | |
| SCHEMBL7700411 | 0.81 | CCR2 (0.51) | CCR2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079190-A1 | 3-SUBSTITUTED INDOLES AS CHEMOKINE ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-10-10 | — | — | WO | disclosed |