Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.55 |
| ▸ | RAB9A | P51151 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251370 | 0.83 | NPC1 (0.68) | NPC1RAB9AALDH1A1KDM4EGPR55 | |
| SCHEMBL119941 | 0.79 | DDAH1 (0.66) | NPC1RAB9ASMN1; SMN2PKMGAA | |
| SCHEMBL4066174 | 0.79 | CNR2 (0.48) | — | |
| Fluoride SCHEMBL28200576 | 0.78 | DDAH1 (0.63) | NPC1RAB9ASMN1; SMN2PKMGAA | |
| Hydrochloric Acid SCHEMBL5263367 | 0.78 | DDAH1 (0.63) | NPC1RAB9ASMN1; SMN2PKMGAA | |
| SCHEMBL12472220 | 0.77 | NPC1 (0.63) | NPC1RAB9AALDH1A1KDM4EGPR55 | |
| SCHEMBL7697312 | 0.77 | GAA (0.53) | NPC1RAB9ASMN1; SMN2PKMGAA | |
| SCHEMBL227743 | 0.76 | NPC1 (0.78) | NPC1RAB9AALDH1A1KDM4EGPR55 | |
| SCHEMBL28116783 | 0.74 | NPC1 (0.72) | NPC1RAB9AALDH1A1KDM4EGPR55 | |
| SCHEMBL297468 | 0.73 | RAB9A (0.67) | NPC1RAB9AALDH1A1KDM4EGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002092575-A1 | BENZIMIDAZOLE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS, INC. (US) | 2002-11-21 | — | — | WO | disclosed |