Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697059 | 0.86 | CHRNB2 (0.56) | PPIDLMNAALDH1A1KDM4ECHRNB2 | |
| SCHEMBL7696324 | 0.81 | CHRNB2 (0.51) | LMNAALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL4509905 | 0.80 | PPID (0.57) | PPIDLMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28261473 | 0.79 | LMNA (0.58) | LMNAALDH1A1KDM4ESCN1ASCN2A | |
| SCHEMBL27375291 | 0.76 | CHRNB2 (0.54) | LMNACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL396552 | 0.75 | TSHR (0.69) | LMNAALDH1A1KDM4ESCN1ASCN2A | |
| SCHEMBL2107033 | 0.74 | ALDH1A1 (0.54) | PPIDALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL28547271 | 0.74 | SCN1A (0.58) | LMNAALDH1A1KDM4ESCN1ASCN2A | |
| Bicarbonate SCHEMBL27449726 | 0.73 | TSHR (0.67) | LMNAALDH1A1KDM4ESCN1ASCN2A | |
| SCHEMBL1222232 | 0.73 | ALDH1A1 (0.58) | PPIDLMNAALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |