Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693804 | 0.92 | IKBKB (0.45) | IKBKBGPBAR1KDM4EALDH1A1MAPT | |
| SCHEMBL7703225 | 0.90 | IKBKB (0.46) | IKBKBGPBAR1KDM4EALDH1A1LMNA | |
| SCHEMBL7704986 | 0.89 | HSD17B2 (0.42) | IKBKBKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7695157 | 0.86 | IKBKB (0.48) | IKBKBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7701500 | 0.83 | GPBAR1 (0.47) | IKBKBGPBAR1KDM4EALDH1A1LMNA | |
| SCHEMBL7703305 | 0.81 | GPBAR1 (0.53) | IKBKBGPBAR1KDM4EALDH1A1LMNA | |
| SCHEMBL7694123 | 0.79 | KDM4E (0.53) | IKBKBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7696153 | 0.78 | ALDH1A1 (0.47) | IKBKBKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7699232 | 0.78 | ALDH1A1 (0.47) | IKBKBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7699727 | 0.78 | IKBKB (0.42) | IKBKBALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |