SCHEMBL770343

SCHEMBL770343

FC(F)(F)CC(F)(F)C(F)(F)OCc1ccc(-c2ccc(COC(F)(F)C(F)(F)CC(F)(F)F)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.38
AGXT P21549 3/20 0.38
HDAC1 Q13547 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
PTPN1 P18031 1/20 0.33
ALDH1A1 P00352 1/20 0.32
NAAA Q02083 1/20 0.31
MAOB P27338 1/20 0.31
GSTP1 P09211 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL769993 0.92 IDO1 (0.33) IDO1AGXTHDAC1HDAC8HDAC6
SCHEMBL2223979 0.92 KIF11 (0.41) IDO1AGXTPTPN1ALDH1A1
SCHEMBL770340 0.76 IDO1 (0.33) IDO1AGXTHDAC1HDAC8HDAC6
SCHEMBL1081720 0.73 CA1 (0.39) IDO1AGXTHDAC1HDAC8HDAC6
SCHEMBL770342 0.70 IDO1 (0.36) IDO1AGXTNAAAMAOB
SCHEMBL769990 0.69
SCHEMBL2223968 0.69 KIF11 (0.40)
SCHEMBL2223994 0.69 TACR1 (0.38) GSTP1
SCHEMBL770086 0.67 CA1 (0.35) IDO1AGXT
SCHEMBL12805079 0.67 KIF11 (0.41) IDO1AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516389-B1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES CO (US) 2016-02-17 EP disclosed
US-9045400-B2 Fluorinated aromatic bis(acyl)-containing compounds and polyesters prepared therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-06-02 US disclosed
US-8975436-B2 Fluorinated arylene-containing compounds, methods, and polymers prepared therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-03-10 US disclosed
EP-2440520-B1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES CO (US) 2014-11-19 EP disclosed
US-20140163250-A1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-06-12 US disclosed
EP-2516389-A1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM 3M Innovative Properties Company (US) 2012-10-31 EP disclosed
US-20120252997-A1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2012-10-04 US disclosed
EP-2440520-A1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM 3M Innovative Properties Company (US) 2012-04-18 EP disclosed
US-20120071626-A1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2012-03-22 US disclosed
WO-2011087717-A1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-07-21 WO disclosed
WO-2011005396-A1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140163250-A1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM NOTUM, FFAR1, FFAR2 IDO1 4249/4885AGXT 2263/4885HDAC1 1593/4885
US-20120071626-A1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM AFF1, AFF2, FFAR2 IDO1 4213/4885AGXT 3549/4885HDAC1 1627/4885
US-20120252997-A1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM WASF2, PFAS, FLI1 IDO1 3252/4885AGXT 3764/4885HDAC1 2120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.