Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | GLI1 | P08151 | 1/20 | 0.48 |
| ▸ | GLI2 | P10070 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517509 | 0.93 | CTSL (0.59) | L3MBTL1KMT2ASLC7A5MEN1GAA | |
| SCHEMBL7520851 | 0.92 | PTGS2 (0.51) | L3MBTL1KMT2ASLC7A5MEN1GAA | |
| SCHEMBL7515768 | 0.92 | PTGS2 (0.51) | L3MBTL1KMT2ASLC7A5MEN1GAA | |
| SCHEMBL7712131 | 0.90 | CTSL (0.54) | L3MBTL1KMT2ASLC7A5MEN1GAA | |
| SCHEMBL7709387 | 0.88 | CTSL (0.55) | L3MBTL1KMT2AMEN1GAACTSL | |
| SCHEMBL7709355 | 0.87 | ESRRG (0.51) | L3MBTL1KMT2ASLC7A5MEN1GAA | |
| SCHEMBL7709190 | 0.86 | PTGS2 (0.52) | KMT2ASLC7A5MEN1GAATRPV1 | |
| SCHEMBL7703714 | 0.86 | PTGS2 (0.54) | KMT2ASLC7A5MEN1GAATRPV1 | |
| SCHEMBL7563980 | 0.85 | MEN1 (0.55) | KMT2ASLC7A5MEN1GAACTSL | |
| SCHEMBL7521000 | 0.85 | PTGS2 (0.53) | KMT2ASLC7A5MEN1GAAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |