Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520851 | 0.96 | PTGS2 (0.51) | CTSLGRIA1CA1CA2CA7 | |
| SCHEMBL7515768 | 0.96 | PTGS2 (0.51) | CTSLGRIA1CA1CA2CA7 | |
| SCHEMBL7517509 | 0.96 | CTSL (0.59) | CTSLGRIA1CA1CA2L3MBTL1 | |
| SCHEMBL7563980 | 0.89 | MEN1 (0.55) | CTSLGRIA1CA1CA2CA7 | |
| SCHEMBL7703692 | 0.88 | L3MBTL1 (0.57) | CTSLGRIA1CA1CA2L3MBTL1 | |
| SCHEMBL7709781 | 0.88 | MEN1 (0.56) | GRIA1CA1CA2CA7CA9 | |
| SCHEMBL7521380 | 0.87 | CTSS (0.50) | CTSLCA1CA2CA7CA9 | |
| SCHEMBL7712131 | 0.85 | CTSL (0.54) | CTSLCA1CA2CA7CA9 | |
| SCHEMBL7554886 | 0.85 | GRIA1 (0.55) | GRIA1GAAMAPTSMN1; SMN2CHRND | |
| SCHEMBL7516942 | 0.84 | CTSL (0.53) | CTSLGRIA1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |