Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 12/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 7/20 | 0.38 |
| ▸ | CCR6 | P51684 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709778 | 0.87 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ARAB9ANPSR1 | |
| SCHEMBL7706701 | 0.78 | MEN1 (0.47) | ALDH1A1MEN1KMT2ARAB9ANPSR1 | |
| SCHEMBL8677385 | 0.72 | ALDH1A1 (0.59) | ALDH1A1RAB9ALMNAHTTMAPT | |
| SCHEMBL7706705 | 0.69 | MEN1 (0.44) | ALDH1A1MEN1KMT2ARAB9ANPSR1 | |
| SCHEMBL7706804 | 0.68 | HTT (0.47) | ALDH1A1MEN1KMT2ARAB9ANPSR1 | |
| SCHEMBL13495357 | 0.66 | MEN1 (0.68) | ALDH1A1MEN1KMT2ARAB9ANPSR1 | |
| SCHEMBL13621750 | 0.65 | POLB (0.64) | ALDH1A1MEN1KMT2ARAB9ANPSR1 | |
| SCHEMBL7706801 | 0.65 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL13982812 | 0.65 | CYP3A4 (0.43) | ALDH1A1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL7709710 | 0.64 | MEN1 (0.47) | ALDH1A1MEN1KMT2ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |