Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703735 | 0.83 | KDM4E (0.44) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7709480 | 0.81 | ALDH1A1 (0.62) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7703381 | 0.78 | BCHE (0.39) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7709865 | 0.75 | ALDH1A1 (0.37) | MEN1KMT2AMAPTSMN1; SMN2HPGD | |
| SCHEMBL7706744 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7709612 | 0.73 | TYMS (0.51) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7709632 | 0.71 | CYP1B1 (0.58) | MEN1KMT2ANPC1MAPTL3MBTL1 | |
| SCHEMBL7712213 | 0.70 | PRMT1 (0.46) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL13495357 | 0.70 | MEN1 (0.68) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7703689 | 0.68 | ALDH1A1 (0.41) | MEN1KMT2ARAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |