Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 11/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712259 | 0.82 | ALDH1A1 (0.66) | ALDH1A1NPSR1MAPTCYP1A2CYP2C9 | |
| SCHEMBL7703729 | 0.81 | MEN1 (0.44) | ALDH1A1NPSR1MAPTCYP1A2CYP2C9 | |
| SCHEMBL7709761 | 0.78 | ALDH1A1 (0.60) | ALDH1A1NPSR1MAPTCYP1A2CYP2C9 | |
| SCHEMBL7703797 | 0.78 | ALDH1A1 (0.44) | ALDH1A1NPSR1MAPTMEN1KMT2A | |
| SCHEMBL7703689 | 0.77 | ALDH1A1 (0.41) | ALDH1A1NPSR1MAPTCYP1A2CYP2C9 | |
| SCHEMBL14463542 | 0.76 | ALDH1A1 (0.60) | ALDH1A1NPSR1MAPTCYP1A2CYP2C9 | |
| SCHEMBL7703730 | 0.75 | ALDH1A1 (0.36) | ALDH1A1NPSR1MAPTCYP1A2CYP2C9 | |
| SCHEMBL12673015 | 0.75 | ALDH1A1 (0.59) | ALDH1A1NPSR1MAPTCYP1A2CYP2C9 | |
| SCHEMBL12660329 | 0.74 | ALDH1A1 (0.58) | ALDH1A1NPSR1MAPTCYP1A2CYP2C9 | |
| SCHEMBL12672923 | 0.70 | ALDH1A1 (0.53) | ALDH1A1NPSR1MAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |
| EP-0939754-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1998019648-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |