Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 2/20 | 0.32 |
| ▸ | CASP4 | P49662 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 2/20 | 0.32 |
| ▸ | CASP9 | P55211 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709865 | 0.87 | ALDH1A1 (0.37) | ALDH1A1CASP6MEN1KMT2APOLB | |
| SCHEMBL7703730 | 0.83 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL7703381 | 0.77 | BCHE (0.39) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL7703689 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL7703729 | 0.74 | MEN1 (0.44) | ALDH1A1CASP6MEN1KMT2APOLB | |
| SCHEMBL7709521 | 0.73 | ALDH1A1 (0.49) | ALDH1A1TSHRTDP1KDM1A | |
| SCHEMBL7703715 | 0.65 | TERT (0.37) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL7706734 | 0.63 | MEN1 (0.47) | CASP6MEN1KMT2APOLBKDM4E | |
| SCHEMBL7709472 | 0.63 | MEN1 (0.40) | ALDH1A1CASP6MEN1KMT2APOLB | |
| SCHEMBL28944543 | 0.63 | ALDH1A1 (0.37) | ALDH1A1CASP6MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |