Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.54 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.54 |
| ▸ | KLK7 | P49862 | 1/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706813 | 0.84 | MAPT (0.48) | ERCC1FEN1ERCC4KLK7FTO | |
| SCHEMBL7709467 | 0.82 | EPHX1 (0.50) | ERCC1FEN1ERCC4KLK7FTO | |
| SCHEMBL7703367 | 0.75 | ERCC1 (0.70) | ERCC1FEN1ERCC4FTOKDM4E | |
| SCHEMBL7709776 | 0.74 | KLK7 (0.53) | ERCC1FEN1ERCC4KLK7KDM4E | |
| SCHEMBL132760 | 0.73 | ERCC1 (1.00) | ERCC1FEN1ERCC4KDM4EMEN1 | |
| SCHEMBL29410043 | 0.73 | ERCC1 (1.00) | ERCC1FEN1ERCC4KDM4EMEN1 | |
| SCHEMBL7706718 | 0.72 | ERCC1 (0.70) | ERCC1FEN1ERCC4KDM4EMEN1 | |
| SCHEMBL7706742 | 0.72 | ERCC1 (0.70) | ERCC1FEN1ERCC4KDM4EMEN1 | |
| SCHEMBL7709436 | 0.72 | KLK7 (0.61) | KLK7FTOKDM4EMEN1KMT2A | |
| SCHEMBL7703805 | 0.71 | MPO (0.73) | ERCC1FEN1ERCC4FTOKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | claimed |