Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709467 | 0.93 | EPHX1 (0.50) | MAPTERCC1FEN1ERCC4HPGD | |
| SCHEMBL7703767 | 0.84 | ERCC1 (0.54) | MAPTERCC1FEN1ERCC4HPGD | |
| SCHEMBL5457321 | 0.75 | FTO (0.66) | MAPTHPGDPOLBFTOCYP1A2 | |
| SCHEMBL14557208 | 0.72 | KLK7 (0.57) | MAPTHPGDPOLBKLK7FTO | |
| SCHEMBL7703367 | 0.71 | ERCC1 (0.70) | MAPTERCC1FEN1ERCC4HPGD | |
| SCHEMBL14423982 | 0.70 | EPHX1 (0.79) | MAPTPOLBEPHX1CYP1A2CYP2C19 | |
| SCHEMBL7703805 | 0.70 | MPO (0.73) | MAPTERCC1FEN1ERCC4HPGD | |
| SCHEMBL7709776 | 0.70 | KLK7 (0.53) | MAPTERCC1FEN1ERCC4HPGD | |
| SCHEMBL5123962 | 0.69 | KDM4E (0.64) | MAPTHPGDKLK7FTOCYP1B1 | |
| SCHEMBL7706739 | 0.69 | ERCC1 (0.57) | MAPTERCC1FEN1ERCC4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | claimed |