Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706813 | 0.93 | MAPT (0.48) | EPHX1MEN1KMT2ARXFP1ERCC1 | |
| SCHEMBL7703767 | 0.82 | ERCC1 (0.54) | MEN1KMT2AERCC1FEN1ERCC4 | |
| SCHEMBL14557208 | 0.75 | KLK7 (0.57) | MEN1KMT2ARXFP1ALDH1A1HTT | |
| SCHEMBL5457321 | 0.73 | FTO (0.66) | MEN1KMT2ARXFP1ALDH1A1HTT | |
| SCHEMBL14424451 | 0.72 | EPHX1 (0.89) | EPHX1MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL19872906 | 0.70 | MEN1 (0.53) | MEN1KMT2ARXFP1ALDH1A1HTT | |
| SCHEMBL13829158 | 0.70 | ERCC1 (0.50) | MEN1KMT2ARXFP1ERCC1FEN1 | |
| SCHEMBL13327255 | 0.69 | TDP1 (0.59) | MEN1KMT2AALDH1A1HTTPOLB | |
| SCHEMBL7703367 | 0.69 | ERCC1 (0.70) | MEN1KMT2AERCC1FEN1ERCC4 | |
| SCHEMBL29713417 | 0.69 | ERCC1 (0.49) | MEN1KMT2ARXFP1ERCC1FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | claimed |