Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 10/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.39 |
| ▸ | USP2 | O75604 | 5/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.36 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706721 | 0.85 | HTT (0.50) | ALDH1A1KDM4EGAABRD4MEN1 | |
| SCHEMBL7706744 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAABRD4MEN1 | |
| SCHEMBL7709480 | 0.78 | ALDH1A1 (0.62) | ALDH1A1GAAMEN1KMT2AHTT | |
| SCHEMBL7703741 | 0.69 | MDM4 (0.39) | ALDH1A1KDM4EGAABRD4KMT2A | |
| SCHEMBL7709632 | 0.68 | CYP1B1 (0.58) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL7703735 | 0.67 | KDM4E (0.44) | ALDH1A1KDM4EMEN1KMT2AUSP2 | |
| SCHEMBL7709992 | 0.67 | BRD4 (0.45) | ALDH1A1BRD4MEN1KMT2AUSP2 | |
| SCHEMBL7709561 | 0.67 | BRD1 (0.40) | ALDH1A1KDM4EBRD4KMT2ALMNA | |
| SCHEMBL7712199 | 0.66 | KMT2A (0.64) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL5964469 | 0.66 | ALDH1A1 (0.71) | ALDH1A1KDM4EGAABRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |