Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8164857 | 0.90 | GRM2 (0.32) | GRM2GRM3CTSSCTSKCTSL | |
| SCHEMBL2637609 | 0.88 | CYP2D6 (0.35) | GRM2GRM3CTSSCTSKCTSL | |
| SCHEMBL7707030 | 0.83 | CTSS (0.33) | CTSSCTSKCTSL | |
| SCHEMBL7706396 | 0.76 | CTSS (0.35) | GRM2GRM3CTSSCTSKCTSL | |
| SCHEMBL8169580 | 0.76 | CTSS (0.35) | GRM2GRM3CTSSCTSKCTSL | |
| SCHEMBL2410161 | 0.74 | MMP8 (0.49) | — | |
| SCHEMBL1341696 | 0.73 | ALDH1A1 (0.37) | CTSSCTSK | |
| SCHEMBL13020680 | 0.71 | TSHR (0.32) | CTSS | |
| SCHEMBL8466452 | 0.70 | — | — | |
| SCHEMBL4734754 | 0.70 | MCL1 (0.34) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938509-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SPA (IT) | 2002-11-20 | — | — | EP | claimed |