Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.52 |
| ▸ | ITGAL | P20701 | 3/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole SCHEMBL27577896 | 1.00 | ALDH1A1 (0.59) | ALDH1A1ALOX15ACESMN1; SMN2ITGB2 | |
| SCHEMBL120493 | 0.91 | ALOX15 (0.67) | ALDH1A1ALOX15ACESMN1; SMN2ITGB2 | |
| SCHEMBL29402200 | 0.91 | ALOX15 (0.67) | ALDH1A1ALOX15ACESMN1; SMN2ITGB2 | |
| SCHEMBL5519036 | 0.91 | ALOX15 (0.67) | ALDH1A1ALOX15ACESMN1; SMN2ITGB2 | |
| SCHEMBL120495 | 0.91 | ALOX15 (0.67) | ALDH1A1ALOX15ACESMN1; SMN2ITGB2 | |
| Abrine (L) SCHEMBL27479904 | 0.86 | ALOX15 (0.60) | ALDH1A1ALOX15ACESMN1; SMN2ITGB2 | |
| Bromobenzene SCHEMBL27477821 | 0.85 | FPR2 (0.64) | ALDH1A1ALOX15ACESMN1; SMN2ITGB2 | |
| Dl-Tryptophan SCHEMBL1981755 | 0.80 | KMT2A (0.80) | ALDH1A1ALOX15SMN1; SMN2KDM4EMAPT | |
| Tryptophan SCHEMBL1981758 | 0.80 | KMT2A (0.80) | ALDH1A1ALOX15SMN1; SMN2KDM4EMAPT | |
| D-Tryptophan SCHEMBL16390702 | 0.80 | KMT2A (0.80) | ALDH1A1ALOX15SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355416-B1 | A NONRADIOACTIVE TRACER METHOD TO DETERMINE DNA SYNTHESIS BY ADMINISTERING STABLE ISOTOPE LABELLED PRECURSORS TO A SAMPLE THAT CONTAINS REPLICATING DNA WHICH IS INCORPORATED BY METABOLIC SALVAGE PATHWAY; DETECT THE ISOTOPE BY SPECTROMETER | THE GEORGE WASHINGTON UNIVERSITY | 2002-03-12 | — | — | US | disclosed |