Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.45 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.45 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.45 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16890383 | 0.89 | PGR (0.46) | LTA4HCYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL20101688 | 0.89 | CYP1A2 (0.57) | CYP11B1CYP11B2CYP17A1HDAC8CYP1A2 | |
| SCHEMBL16561425 | 0.80 | HDAC8 (0.49) | CYP11B1CYP11B2CYP17A1HDAC8CYP1A2 | |
| SCHEMBL12989388 | 0.80 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP17A1HDAC8CYP1A2 | |
| SCHEMBL28550067 | 0.78 | CYP1A2 (0.56) | CYP1A2CYP2A6CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9781864 | 0.76 | CYP1A2 (0.53) | CYP11B1CYP11B2CYP17A1HDAC8CYP1A2 | |
| SCHEMBL5286981 | 0.76 | BRD4 (0.55) | CYP11B1CYP11B2CYP1A2CYP2A6CYP3A4 | |
| SCHEMBL6013084 | 0.75 | L3MBTL1 (0.55) | LTA4HCYP1A2CYP2A6CYP2C9CYP2C19 | |
| SCHEMBL8125066 | 0.75 | HDAC8 (0.54) | CYP11B1CYP11B2HDAC8CYP1A2CYP2A6 | |
| SCHEMBL3598954 | 0.75 | ALDH1A1 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |