SCHEMBL7704471

SCHEMBL7704471

CCC(=O)OC(=O)C(C)CS

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
CYP1A2 P05177 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
BLM P54132 1/20 0.35
WRN Q14191 1/20 0.35
HIF1A Q16665 1/20 0.35
NAAA Q02083 1/20 0.34
ENPEP Q07075 2/20 0.33
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7704470 0.85 ENPEP (0.38) CYP1A2ENPEP
SCHEMBL8837532 0.83 ENPEP (0.35) ENPEPTSHRHSD17B10
SCHEMBL11792511 0.81 NAAA (0.37) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL15259527 0.79 NAAA (0.35) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL27886734 0.79 ALDH1A1 (0.41) ALDH1A1ENPEPTSHRHSD17B10
SCHEMBL28353497 0.79 NAAA (0.35) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL27687013 0.77 CYP1A2 (0.34) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL14935428 0.77 NAAA (0.39) ALDH1A1NAAATSHR
SCHEMBL7707533 0.76 NAAA (0.37) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL818188 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6361872-B1 CORROSION RESISTANCE FOR METAL SURFACES WITH MERCAPTO COMPOUNDS AND CURING AGENTS METAL COATINGS INTERNATIONAL INC. 2002-03-26 US disclosed
WO-1999060187-A1 METAL SURFACE TREATMENT AGENTS, METHODS OF TREATING METAL SURFACES AND PRE-COATED STEEL SHEETS DACRAL S.A. (FR) 1999-11-25 WO disclosed
US-5625075-A Metal radionuclide chelating compounds for improved chelation kinetics NEORX CORPORATION (US) 1997-04-29 US disclosed
US-5436352-A Metal radionuclide chelating compounds for improved chelation kinetics NEORX CORPORATION (US) 1995-07-25 US disclosed
EP-0344724-B1 METAL RADIONUCLIDE CHELATING COMPOUNDS FOR IMPROVED CHELATION KINETICS NEORX CORPORATION (US) 1993-08-11 EP disclosed
US-5075099-A Metal radionuclide chelating compounds for improved chelation kinetics NEORX CORPORATION (US) 1991-12-24 US disclosed
US-4988496-A Metal radionuclide chelating compounds for improved chelation kinetics NEORX CORPORATION (US) 1991-01-29 US disclosed
EP-0344724-A2 Metal radionuclide chelating compounds for improved chelation kinetics NEORX CORPORATION (US) 1989-12-06 EP disclosed