Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 18/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704508 | 0.85 | GPR6 (0.38) | — | |
| SCHEMBL7700514 | 0.80 | VCP (0.59) | VCP | |
| SCHEMBL7459618 | 0.79 | VCP (0.54) | VCP | |
| SCHEMBL7141549 | 0.77 | RORC (0.37) | — | |
| SCHEMBL7139792 | 0.75 | KDM4D (0.36) | — | |
| SCHEMBL7703096 | 0.72 | VCP (0.42) | VCP | |
| SCHEMBL7703665 | 0.71 | VCP (0.36) | VCP | |
| SCHEMBL7699300 | 0.69 | VCP (0.45) | VCP | |
| SCHEMBL7465214 | 0.68 | VCP (0.45) | VCP | |
| SCHEMBL7703613 | 0.67 | VCP (0.47) | VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224174-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001029011-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-26 | — | — | WO | disclosed |