Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 11/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 10/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5976514 | 0.93 | MAPK10 (0.43) | MAPK10MAPK9MAPK8 | |
| SCHEMBL2886459 | 0.80 | MAPK10 (0.70) | MAPK10MAPK9MAPK8 | |
| SCHEMBL4187928 | 0.79 | ILK (0.41) | — | |
| SCHEMBL4026579 | 0.78 | MAPK10 (0.71) | MAPK10MAPK9MAPK8 | |
| Acetonitrile SCHEMBL7707689 | 0.75 | MAPK10 (0.67) | MAPK10MAPK9MAPK8 | |
| SCHEMBL4968704 | 0.74 | MAPK10 (0.49) | MAPK10MAPK9MAPK8 | |
| SCHEMBL4201475 | 0.74 | MAPK10 (0.48) | MAPK10MAPK9MAPK8 | |
| SCHEMBL4188154 | 0.73 | MAPK10 (0.44) | MAPK10MAPK9MAPK8 | |
| SCHEMBL4192590 | 0.73 | MAPK10 (0.44) | MAPK10MAPK9MAPK8 | |
| SCHEMBL4190708 | 0.72 | USP2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | claimed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | claimed |