Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 8/20 | 0.33 |
| ▸ | PPARG | P37231 | 7/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702693 | 0.87 | KMT2A (0.38) | PPARGCYP2C9CYP3A4KDM4EALDH1A1 | |
| SCHEMBL7700374 | 0.81 | ALDH1A1 (0.32) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL7693804 | 0.79 | IKBKB (0.45) | IKBKBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7695157 | 0.77 | IKBKB (0.48) | IKBKBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7704549 | 0.76 | ALDH1A1 (0.39) | IKBKBCYP2C9CYP3A4KDM4EALDH1A1 | |
| SCHEMBL7698726 | 0.76 | LMNA (0.47) | IKBKBEGFR | |
| SCHEMBL7694123 | 0.74 | KDM4E (0.53) | IKBKBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7699232 | 0.73 | ALDH1A1 (0.47) | IKBKBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7705474 | 0.72 | IKBKB (0.42) | IKBKBKDM4EALDH1A1HPGD | |
| SCHEMBL7693979 | 0.72 | IKBKB (0.42) | IKBKBKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |