Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371389 | 0.83 | ESR2 (0.41) | ALDH1A1HPGDL3MBTL1CYP2A6CYP2B6 | |
| SCHEMBL7704868 | 0.76 | GSTP1 (0.49) | MAOAMAOB | |
| SCHEMBL5795387 | 0.75 | ACHE (0.36) | ALDH1A1HPGDMAOBTDP1CYP2C9 | |
| SCHEMBL7699446 | 0.71 | GSTP1 (0.50) | ALDH1A1HPGDSLC6A4TDP1CYP1A2 | |
| SCHEMBL11763851 | 0.71 | MAOA (0.46) | ALDH1A1HPGDMAOAMAOBBCL2 | |
| SCHEMBL9568786 | 0.70 | MAPT (0.48) | ALDH1A1HPGDMAOAMAOBBCL2 | |
| SCHEMBL10706537 | 0.70 | MAPT (0.48) | ALDH1A1HPGDMAOAMAOBBCL2 | |
| SCHEMBL3282692 | 0.70 | MAPT (0.44) | ALDH1A1HPGDMAOAMAOBBCL2 | |
| SCHEMBL17065474 | 0.70 | MAPT (0.48) | ALDH1A1HPGDMAOAMAOBBCL2 | |
| SCHEMBL2754909 | 0.70 | MAOA (0.54) | ALDH1A1HPGDMAOAMAOBBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |