Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708204 | 0.75 | IDO1 (0.39) | IDO1 | |
| SCHEMBL7094224 | 0.74 | ALDH1A1 (0.34) | IDO1 | |
| SCHEMBL7705014 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL7704928 | 0.72 | SMYD3 (0.35) | IDO1 | |
| SCHEMBL7091666 | 0.71 | PFKFB3 (0.33) | IDO1 | |
| Hydrochloric Acid SCHEMBL6989617 | 0.70 | IDO1 (0.33) | IDO1 | |
| SCHEMBL7093745 | 0.70 | KDM4E (0.34) | IDO1 | |
| SCHEMBL7704829 | 0.69 | EPHX2 (0.31) | — | |
| SCHEMBL7705017 | 0.65 | ALDH1A1 (0.34) | IDO1 | |
| SCHEMBL7000036 | 0.65 | NR3C1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365736-B1 | TREATMENT OF NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS AND FOR ACTIVITY AS NO-SYNTHASES (NOS) INHIBITORS. | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |