Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 13/20 | 0.50 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.46 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.45 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695533 | 0.95 | ADCY8 (0.47) | DGAT1RUVBL1ADCY8ADCY1TMPRSS4 | |
| SCHEMBL7701437 | 0.93 | DGAT1 (0.44) | DGAT1RUVBL1ADCY8ADCY1TMPRSS4 | |
| SCHEMBL7699293 | 0.89 | KDM4E (0.53) | DGAT1RUVBL1ADCY8ADCY1TMPRSS4 | |
| SCHEMBL7696428 | 0.84 | STAT3 (0.55) | DGAT1MAPTKDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL7704697 | 0.81 | ADCY8 (0.45) | DGAT1RUVBL1ADCY8ADCY1TMPRSS4 | |
| SCHEMBL7693922 | 0.80 | KDM4E (0.60) | DGAT1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7700043 | 0.79 | TACR1 (0.49) | DGAT1 | |
| SCHEMBL7697491 | 0.78 | HDAC4 (0.49) | DGAT1MAPT | |
| SCHEMBL7701281 | 0.78 | MAPT (0.49) | DGAT1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL7698238 | 0.78 | ALDH1A1 (0.55) | DGAT1MAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |