Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700098 | 0.87 | GSTP1 (0.50) | GSTP1PTGS2LTA4HTSHRNCOA1 | |
| SCHEMBL5392376 | 0.87 | LTA4H (0.41) | GSTP1ALDH1A1L3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL16720564 | 0.79 | NOTUM (0.39) | GSTP1ALDH1A1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL3938740 | 0.79 | ACACB (0.37) | GSTP1MAPTPTGS2LTA4HTSHR | |
| SCHEMBL7707290 | 0.79 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL11530878 | 0.78 | NCOA1 (0.49) | GSTP1PTGS2LTA4HTSHRNCOA1 | |
| SCHEMBL6372462 | 0.76 | GSTP1 (0.42) | GSTP1ALDH1A1MAPTLTA4HTSHR | |
| SCHEMBL4282895 | 0.75 | PDE10A (0.41) | L3MBTL1CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL17811579 | 0.73 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL4279106 | 0.73 | HSD17B1 (0.39) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |