Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10623223 | 0.83 | PTGS2 (0.38) | ALDH1A1CYP1A2CYP3A4TDP1MAPK1 | |
| SCHEMBL695988 | 0.83 | PDCD1 (0.39) | ALDH1A1MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL7704751 | 0.79 | GSTP1 (0.38) | ALDH1A1L3MBTL1MAPTKDM4ECYP1A2 | |
| SCHEMBL2565144 | 0.77 | TDP1 (0.35) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| SCHEMBL17811579 | 0.77 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPTKDM4ECYP1A2 | |
| SCHEMBL7700044 | 0.76 | GSTP1 (0.49) | SMN1; SMN2PTGS2 | |
| SCHEMBL15681412 | 0.76 | CA12 (0.47) | ALDH1A1L3MBTL1MAPTKDM4ECYP1A2 | |
| SCHEMBL22079011 | 0.75 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPTKDM4ECYP1A2 | |
| SCHEMBL14280992 | 0.75 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPTKDM4ECYP1A2 | |
| SCHEMBL13854541 | 0.75 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPTKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216285-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | Ciba SC Holding AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019939-A1 | FLUORESCENT MALEIMIDES AND USES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |