Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704572 | 0.89 | ICMT (0.48) | ICMTPPARGPPARA | |
| SCHEMBL2590889 | 0.85 | GABRA1 (0.44) | ICMTGAANPSR1 | |
| SCHEMBL10339218 | 0.85 | AKR1B1 (0.46) | ICMTPLA2G2AGAANPSR1 | |
| Benzene SCHEMBL15265833 | 0.83 | AKR1B1 (0.50) | PLA2G2AGAANPSR1 | |
| SCHEMBL4032382 | 0.82 | AKR1B1 (0.57) | PPARGPPARA | |
| SCHEMBL27734152 | 0.79 | L3MBTL1 (0.53) | ICMTGAANPSR1 | |
| Butane SCHEMBL9614624 | 0.78 | AKR1B1 (0.59) | ICMTGAANPSR1 | |
| SCHEMBL28135229 | 0.78 | ICMT (0.41) | ICMTSIRT1PRKCI | |
| Hydrogen Peroxide SCHEMBL29092952 | 0.78 | LIPG (0.45) | PPARGPPARAGAA | |
| Ethane SCHEMBL28047378 | 0.78 | KDM4E (0.41) | ICMTGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |
| US-6353128-B1 | FOR TREATMENT OF CONDITIONS SUCH AS SEPTIC SHOCK. | ELI LILLY AND COMPANY | 2002-03-05 | — | — | US | disclosed |
| EP-0833637-A4 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST | MERCK & CO INC (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0833637-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST | Merck & Co., Inc. (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996040136-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST | MERCK & CO., INC. (US) | 1996-12-19 | — | — | WO | disclosed |