Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705061 | 0.89 | MEN1 (0.64) | MAPTALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL7974694 | 0.88 | MAPT (0.63) | MAPTALDH1A1MEN1KMT2AKCNH2 | |
| Hydrochloric Acid SCHEMBL7713479 | 0.87 | MEN1 (0.64) | MAPTALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL7711429 | 0.86 | MAPT (0.76) | MAPTALDH1A1MEN1KMT2AKCNH2 | |
| Hydrochloric Acid SCHEMBL7708501 | 0.85 | MAPT (0.75) | MAPTALDH1A1MEN1KMT2AKCNH2 | |
| Enciprazine SCHEMBL29710915 | 0.84 | MAPT (0.74) | MAPTALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL29074454 | 0.84 | MAPT (0.71) | MAPTALDH1A1MEN1KMT2AKCNH2 | |
| Enciprazine SCHEMBL584730 | 0.84 | MAPT (0.74) | MAPTALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL17313697 | 0.84 | KCNH2 (0.78) | MAPTALDH1A1MEN1KMT2AKCNH2 | |
| Enciprazine SCHEMBL668369 | 0.83 | MAPT (0.76) | MAPTALDH1A1MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358515-B2 | ANTIHYPERTENSIVE PHARMACEUTICAL COMPOSITION; TREATMENT OF GLAUCOMA | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | claimed |
| US-20010008893-A1 | HYDROQUINONE DERIVATIVES | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-19 | — | — | US | claimed |
| EP-0972766-A1 | HYDROQUINONE DERIVATIVES | Senju Pharmaceutical Co., Ltd. (JP) | 2000-01-19 | — | — | EP | claimed |
| US-6358515-B2 | ANTIHYPERTENSIVE PHARMACEUTICAL COMPOSITION; TREATMENT OF GLAUCOMA | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| US-20010008893-A1 | HYDROQUINONE DERIVATIVES | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-19 | — | — | US | disclosed |
| EP-0972766-A1 | HYDROQUINONE DERIVATIVES | Senju Pharmaceutical Co., Ltd. (JP) | 2000-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010008893-A1 | HYDROQUINONE DERIVATIVES | REN, AGTR1, AGTR2 | MAPT 4729/4885ALDH1A1 128/4885MEN1 2775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.