Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | AHCY | P23526 | 1/20 | 0.36 |
| ▸ | POLG | P54098 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699396 | 1.00 | LMNA (0.45) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL14580367 | 1.00 | LMNA (0.45) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL8471133 | 0.81 | LMNA (0.43) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL8470556 | 0.81 | LMNA (0.43) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL6427736 | 0.79 | LMNA (0.46) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL14615870 | 0.78 | TYMP (0.50) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL13970745 | 0.78 | LMNA (0.53) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL3163908 | 0.78 | LMNA (0.53) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL20059072 | 0.78 | TYMP (0.50) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL3163915 | 0.78 | LMNA (0.53) | LMNATYMPSTING1ABCB1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350753-B1 | 2-ACETOXYMETHYL-4-(THYMIN-1'-YL)-1,3,-DIOXOLANE; 2-BENZOYLOXYMETHYL-4-(CYTOSIN-1'-YL)-1,3-DIOXOLANE; ANTIVIRAL AGENTS, PARTICULARY FOR THE TREATMENT OF THE HIV INFECTIONS IN MAMMALS, ESPECIALLY HUMANS | BIOCHEM PHARMA INC. (CA) | 2002-02-26 | — | — | US | disclosed |