Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 4/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6459797 | 0.89 | P2RX7 (0.39) | P2RX7ABCB11DHODHTHRBTHRA | |
| SCHEMBL7135587 | 0.77 | P2RX7 (0.38) | P2RX7ABCB11THRBTHRAMEN1 | |
| SCHEMBL6462166 | 0.76 | P2RX7 (0.38) | P2RX7ABCB11THRBTHRA | |
| SCHEMBL6461284 | 0.76 | P2RX7 (0.35) | P2RX7ABCB11THRBTHRAMEN1 | |
| SCHEMBL6461628 | 0.72 | ADORA2A (0.38) | P2RX7ABCB11THRBTHRABTK | |
| SCHEMBL6459898 | 0.72 | THRB (0.39) | P2RX7ABCB11THRBTHRAMEN1 | |
| SCHEMBL6462754 | 0.72 | P2RX7 (0.41) | P2RX7ABCB11THRBTHRAMEN1 | |
| SCHEMBL6460370 | 0.71 | P2RX7 (0.34) | P2RX7ABCB11THRB | |
| SCHEMBL6460365 | 0.71 | P2RX7 (0.34) | P2RX7ABCB11THRB | |
| SCHEMBL6462226 | 0.70 | P2RX7 (0.46) | P2RX7ABCB11THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020010177-A1 | IL-5 inhibiting 6-azauracil derivatives | JANSSEN CILAG S.A. (FR) | 2002-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010177-A1 | IL-5 inhibiting 6-azauracil derivatives | ALOX5, IL5, IL6ST | P2RX7 880/4885ABCB11 2670/4885DHODH 1300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.