Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CCKAR | P32238 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3870531 | 1.00 | EPHX2 (0.53) | EPHX2CTSSCTSKCTSLCTSB | |
| SCHEMBL10629248 | 0.91 | CTSS (0.52) | EPHX2CTSSCTSKCTSLCTSB | |
| SCHEMBL9797934 | 0.87 | CTSL (0.57) | CTSSCTSKCTSLCTSBIDO1 | |
| SCHEMBL10633866 | 0.85 | CTSL (0.50) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL6454981 | 0.85 | CTSL (0.50) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL8695509 | 0.83 | IDO1 (0.41) | CTSSCTSKCTSLCCKARCCKBR | |
| SCHEMBL11030896 | 0.82 | ACE (0.59) | EPHX2CTSSCTSKCTSLCTSB | |
| SCHEMBL27616185 | 0.82 | ACE (0.59) | EPHX2CTSSCTSKCTSLCTSB | |
| SCHEMBL8577285 | 0.81 | CTSL (0.46) | CTSSCTSKCTSLCTSBIDO1 | |
| SCHEMBL10631067 | 0.81 | CTSL (0.46) | CTSSCTSKCTSLCTSBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342582-B1 | PURIFICATION AND/OR BIOSYNTHESIS OF OLIGOPEPTIDES IN PRESENCE OF A PHENOL OR MIXTURE; DEBLOCKING, AMIDATION; VACCINES, DRUGS, FOOD, AGRICULTURE | RHODIA CHIMIE (FR) | 2002-01-29 | — | — | US | disclosed |
| US-5798443-A | MEDIUM COMPRISING WATER IMMISCIBLE DILUENT AND HYDROXYAROMATIC COMPOUND | RHONE-POULENC CHIMIE (FR) | 1998-08-25 | — | — | US | disclosed |
| US-5789386-A | WATER SOLUBLE ANTITUMOR AGENTS; INJECTABLE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0266950-B1 | Nor-statine and nor-cyclostatine polypeptides | PFIZER (US) | 1993-12-29 | — | — | EP | disclosed |
| US-5034376-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4935405-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| US-4814342-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0266950-A2 | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1988-05-11 | — | — | EP | disclosed |