Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.45 |
| ▸ | SRC | P12931 | 8/20 | 0.43 |
| ▸ | ABL1 | P00519 | 6/20 | 0.43 |
| ▸ | ABL2 | P42684 | 5/20 | 0.43 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701895 | 0.89 | EGFR (0.45) | EGFRSRCABL1ABL2KDR | |
| SCHEMBL8991089 | 0.89 | EGFR (0.45) | EGFRSRCABL1ABL2KDR | |
| SCHEMBL7698503 | 0.87 | HTT (0.43) | EGFRSRCABL1KDRNPC1 | |
| SCHEMBL7696370 | 0.84 | ADORA2A (0.51) | EGFRSRCABL1ABL2KDR | |
| SCHEMBL7704452 | 0.84 | HTT (0.41) | SRCABL1NPC1GALR3S1PR4 | |
| SCHEMBL7705468 | 0.79 | EGFR (0.43) | EGFRSRCABL1ABL2KDR | |
| SCHEMBL8991091 | 0.79 | EGFR (0.43) | EGFRSRCABL1ABL2KDR | |
| SCHEMBL7697684 | 0.79 | ADRA1D (0.41) | EGFRSRCABL1ABL2NPC1 | |
| SCHEMBL8991011 | 0.78 | KDM4E (0.49) | EGFRSRCABL1ABL2KDR | |
| SCHEMBL7701968 | 0.78 | RIPK2 (0.45) | EGFRSRCABL1ABL2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |