Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 5/20 | 0.43 |
| ▸ | EGFR | P00533 | 5/20 | 0.43 |
| ▸ | ABL1 | P00519 | 5/20 | 0.43 |
| ▸ | ABL2 | P42684 | 3/20 | 0.43 |
| ▸ | PDE8B | O95263 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698564 | 0.87 | ADK (0.43) | RIPK2SRCEGFRABL1KDR | |
| SCHEMBL7700930 | 0.85 | MAPT (0.46) | RIPK2SRCEGFRABL1KDR | |
| SCHEMBL7700864 | 0.84 | CFD (0.44) | RIPK2SRCEGFRABL1KDR | |
| SCHEMBL7700385 | 0.84 | ADORA2A (0.52) | SRCEGFRABL1ABL2PIK3CD | |
| SCHEMBL7696329 | 0.84 | ADK (0.41) | SRCEGFRABL1KDRLCK | |
| SCHEMBL20081176 | 0.80 | XDH (0.43) | ABL1CYP19A1 | |
| SCHEMBL7701985 | 0.80 | SLC29A1 (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL7705467 | 0.78 | EGFR (0.45) | RIPK2SRCEGFRABL1ABL2 | |
| SCHEMBL7701895 | 0.78 | EGFR (0.45) | RIPK2SRCEGFRABL1ABL2 | |
| SCHEMBL7703250 | 0.78 | CFD (0.42) | RIPK2SRCEGFRABL1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |