Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 6/20 | 0.41 |
| ▸ | SRC | P12931 | 5/20 | 0.41 |
| ▸ | ABL1 | P00519 | 3/20 | 0.41 |
| ▸ | ABL2 | P42684 | 3/20 | 0.41 |
| ▸ | PDE8B | O95263 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991031 | 0.88 | KDM4E (0.41) | EGFRRIPK2SRCABL1HPGD | |
| SCHEMBL8991143 | 0.87 | HDAC1 (0.46) | HDAC1HDAC6ABL1NPC1RAB9A | |
| SCHEMBL8991302 | 0.87 | ADORA2A (0.49) | EGFRSRCABL1ABL2KDR | |
| SCHEMBL8991275 | 0.85 | FLT3 (0.43) | SRCABL1 | |
| SCHEMBL7701895 | 0.84 | EGFR (0.45) | EGFRRIPK2SRCABL1ABL2 | |
| SCHEMBL7705468 | 0.81 | EGFR (0.43) | EGFRHDAC1HDAC6RIPK2SRC | |
| SCHEMBL8991105 | 0.81 | EIF2AK3 (0.42) | RIPK2SRCABL1KDR | |
| SCHEMBL7705467 | 0.79 | EGFR (0.45) | EGFRRIPK2SRCABL1ABL2 | |
| SCHEMBL8991089 | 0.79 | EGFR (0.45) | EGFRRIPK2SRCABL1ABL2 | |
| SCHEMBL8991284 | 0.79 | KDM4E (0.44) | EGFRSRCABL1ABL2PDE8B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |