Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255425 | 0.79 | CLK1 (0.48) | CSNK1DCSNK1ECLK1DYRK1A | |
| SCHEMBL2989390 | 0.76 | PRKCZ (0.35) | CSNK1DCSNK1ECLK1DYRK1A | |
| SCHEMBL2986767 | 0.76 | CYP19A1 (0.33) | CSNK1DCSNK1ECLK1DYRK1A | |
| SCHEMBL20272949 | 0.73 | CLK1 (0.53) | CSNK1DCSNK1ECLK1DYRK1A | |
| SCHEMBL30520081 | 0.71 | CLK1 (0.47) | CSNK1DCSNK1ECLK1DYRK1A | |
| SCHEMBL5894666 | 0.71 | KDM4E (0.33) | CSNK1DCSNK1ECLK1DYRK1A | |
| Isoquinoline SCHEMBL5264460 | 0.70 | ACHE (0.37) | — | |
| SCHEMBL2385144 | 0.70 | ALDH1A1 (0.65) | CSNK1DCSNK1ECLK1DYRK1A | |
| SCHEMBL31187649 | 0.69 | EGFR (0.48) | — | |
| SCHEMBL5894084 | 0.64 | KDM4E (0.31) | CSNK1DCSNK1ECLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169932-B2 | HIV protease inhibitors, compositions containing the same, their pharmaceutical uses, material for their synthesis | PFIZER INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-6610730-B2 | Viricides; protease inbhibitor | AGOURON PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |